About the SCAD UK and Europe research portal

Spontaneous Coronary Artery Dissection (SCAD) is an unpredictable event with patients usually presenting with a sudden unexpected heart attack. It can affect all age groups and is recognised as a cause of heart attacks in young adults. Both sexes can be affected but it is more common in women, in particular during or soon after pregnancy. Sadly some cases of SCAD are fatal. SCAD results from an acute bleed into the vessel wall of a coronary artery creating a false lumen (FL). This accumulation of blood compresses the true lumen (TL) restricting or abolishing blood flow to the heart muscle. Little is currently known about the underlying cause, optimal treatment and long term prognosis of SCAD.

The SCAD UK and Europe research portal is part of an international collaboration of patients, doctors and scientists to undertake research into this condition. To achieve this we have teamed up with the SCAD research team at the Mayo Clinic (Minnesota, USA) in a collaborative transatlantic partnership. The aim is to improve our understanding of the underlying causes of SCAD, to learn about the natural history of patients with this condition and ultimately to improve the prevention and treatment of SCAD events. To achieve this we need as many patients with this condition as possible to help us to study SCAD.

The SCAD UK and Europe research portal is an initiative of the NIHR Leicester Cardiovascular Biomedical Research Unit. The research and clinical content is reviewed by a team led by Dr David Adlam, a senior lecturer in the Leicester University Department of Cardiovascular Sciences.

If you have had SCAD and wish to participate in research to help understand this condition please register. Our research team will then contact you with further information. Registration does not commit you to participate. If you are a medical professional and have a patient who has had SCAD please advise them of our research program.


This research program has been endorsed by the British Cardiac Intervention Society (BCIS) and the British Cardiovascular Society (BCS).